Computerize Aided Medical Diagnosis system on sickle cell disease is designed to assist in the medical diagnosis of Anemia. The program is based on the assumption that sickle cell is the principal complaint, and that there are no other dominant complaints or symptoms. The reliability of the program obviously depends on the information supplied by the physician and/or patient. Entering incorrect or misleading information will cause erroneous or unreliable results. The program works on the principle of an expert system. The main purpose of this study is to develop Computerized aided medical diagnosis system on sickle cell disease that will show the organs of the blood vessels and also gives detail information about them. The program has to show the pictures of both the internal and external organs. This work is narrowed to both the internal and external blood organs in human body. The project based more on the pictorial representation of the organs and their functions. This program is designed using visual basic 6.0 and Microsoft access.